Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
"All I got was an extra hour on the bus to work, but I can't get a seat at the stadium," she said as she directed cars toward a mall's parking garage in Rio's wealthy southern zone.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Whatever the underlying cause, last year’s extreme warmth in the West meant that Alaska, Arizona, California and Nevada all set temperature records. Some parts of California essentially had no winter last year, with temperatures sometimes running 10 to 15 degrees above normal for the season. The temperature in Anchorage, Alaska’s largest city, never fell below zero in 2014, the first time that has happened in 101 years of record-keeping for the city.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
While the S&P 500 is on track to conclude another stellar year of gains, those who sought to beat the index are poised to finish with a more dubious distinction. According to Lipper, 85% of all active stock mutual fund managers had been trailing their benchmarks through the end of November. In a typical year, there are nearly twice as many managers outperforming, with only around two thirds of funds struggling to catch up. Lipper says this is the worst year for active managers relative to the market in three decades.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Accepting the award, he enthused: 'First off, I want to start off by saying that I'm not really sure how I got this because I've had my album out a few years, but I've got one coming,' before thanking his fans and MTV. Elsewhere, Kendrick Lamar was presented with Best Video, though the rapper was unable to attend the event, instead thanking fans via a video link.
However, the state is also wary of the fast growth in online finance, which is largely unregulated and the risks of systemic crises may be high. Since 2007, 370 P2P lending platforms have failed in China, of which 270 failed in the past year, according to research by Morgan Stanley and Wangdaizhijia, a Chinese research group.
Trends and targets in antiviral phototherapy
Three stricts and three honests: Be strict in morals, power and disciplining oneself; be honest in decisions, business and behavior
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Mrs. May’s government proposed a rule that would publicly shame employers who hired foreign workers. And her first major speech was full of barbs directed against multiculturalism, including a jab against people who claimed to be “citizens of the world,” whom she called “citizens of nowhere.”
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
The highest scoring tournament: 1994 in theUnited Stateswhen 24 teams averaged 2.97 over 52 matches.
Diagnostic technologies for COVID-19: a review
'It is most probably from a mine in South Africa known as Premier mine and now as Cullinan, where most of the blue diamonds are from. Probably in the last 30 years,' Mr Lunel said.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
China’s commercial aerospace ambition has long been known, but a few recent milestones are bringing it closer to realization.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Iron Man was Downey’s only movie of 2013, while Johnson had one huge film, Fast & Furious 6; one big film, G.I. Joe: Retaliation; and two smaller films. Together they added up to $1.3 billion at the global box office.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
"We will set the exact date and location for our operation in consideration of weather conditions, but it will not be publicised," said Park Sang-Hak, a former defector who has led a series of balloon launches
Influenza neuraminidase: A druggable target for natural products
狄娜莎(Tinashe)与德文戴·西尼斯(Devonté Hynes)，《打赌》(Bet)， RCA
A third, combined ranking lists the top 50 schools for executive education, calculated from the customised and open tables.
14. Google Calendar
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Investors have noticed Honda’s troubles. The automaker was one of the very few worldwide to avoid deep losses during the global financial crisis. Still, its common shares are down 17.2% over the past year, while the Nikkei 225 Index is up 7.4% and Toyota Motor shares are up 19.5%.
The Handmaid's Tale
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
In 2016, fear and anger became dominant political emotions in the UK and the US — two of the most important, stable and enduring democracies.
Inhibition of SARS coronavirus helicase by bismuth complexes
The Handmaid's Tale
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
The reading represented a fall of 0.4 points from September and a sub-index on output for the gauge, which primarily tracks larger and state-owned enterprises, fell 1.3 points to 53.4. That for new orders dipped 1.9 points to 52.9.
Well, that’s it, kids: we’re heading home. Chinese shares are down 7 per cent, and thanks to the newly-instituted market circuit breakers, that means the market shuts.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The North has already warned that Park will "pay for his crimes in blood" if copies of the film make it across the border.
On Tuesday, 17-year-old Thomas Sohmers unveiled a new super fast computer server that uses a fraction of the electricity that a normal computer does.He's showing it off at the Open Compute Project (OCP) Summit happening this week in San Francisco.This computer is the first product from Sohmers' startup, REX Computing, created with 52-year-old co-founder and CTO Kurt Keville.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
It is already illegal for employers to discriminate on the basis of race, color, sex, nationality, religion, age, or disability. But a majority of states still don't provide protection to LGBT individuals in the workplace. Apple (AAPL, Fortune 500) CEO Tim Cook wants to put an end to this discrepancy. In a November Wall Street Journal op-ed entitled "Workplace Equality Is Good for Business," Cook urged the passing of a federal law to protect workers from discrimination based on sexual orientation.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
They are also less likely to seek employment in a different sector after graduation. Only 30 per cent changed industry sector compared with nearly two-thirds of full-time MBA students.
Total Program Cost: $176,600
He added that “almost every major Korean company, including Hyundai Motor and AmorePacific, relies heavily on Chinese sales”.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
2.Batman vs Superman: Dawn of Justice
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
As economic growth has slowed, policymakers have become increasingly concerned about the pace of lending. Banking assets increased by more than Rmb72tn ($11tn) last year, according to figures from the banking regulator.
Germanyjust hung four onPortugal. It was a bit of a shocking result, at least from the perspective that most observers expectedPortugalto put up a bit more fight. But it was another relatively high-scoring game at World Cup 2014? Not surprising at all.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
People promoting driverless cars, the most hyped industry segment of the moment, became world leaders in verbiage. Elon Musk claimed to be “laser-focused on achieving full self-driving capability on one integrated platform with an order of magnitude greater safety than the average manually driven car” (ie Tesla cars must stop crashing).
When researchers at the University of Illinois set out to create a device that identifies chemicals by their scent, they didn't settle for the sensitivity of the human nose. Instead, they created an artificial nose that uses the smell of bacteria to identify and diagnose specific diseases.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Coordinated reform of medical services, medical insurance, and the medicine industry
Despite the surge of private wealth in China, the country’s billionaires have not yet cracked the top ranks of global rich lists. Hurun estimates that Mr Wang, China’s richest man and head of the Wanda group, ranks 26th globally.
FKA twigs “Two Weeks” (Young Turks)
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
On Nov. 24 and 25, Sotheby’s auctioned the collection of the fourth-generation Munich dealer Konrad Bernheimer, who owns the historic London gallery Colnaghi. Mr. Bernheimer, 65, has decided to scale down his operations. He is closing his Munich gallery, selling his grand Bavarian home, Marquartstein Castle, and is merging Colnaghi with a fellow London dealer, Coll & Cortes.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
The 2014 ranking of 100 programmes for working senior executives is headed by Trium, runby HEC Paris, the London School of Economics and Stern School of Business at New York University. The top five places continue to be dominated by intercontinental EMBAs.
Although Facebook is blocked in China, Tencent has linked WeChat to Facebook, which means that users outside of China can use the service in conjunction with the world's most popular social network. That is a boon for WeChat in Southeast Asian countries like Indonesia, Thailand and the Philippines, which have large numbers of Facebook users. Tencent has offered WeChat in languages for all three markets.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
The Incredible Jessica James
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
*喜剧类最佳客串女演员：蒂娜?菲(Tina Fey)和艾米?波勒(Amy Poehler)，《周六夜现场》(Saturday Night Live)
Whether of left or right, they present themselves as representatives of the common people against elites and unworthy outsiders; make a visceral connection with followers as charismatic leaders; manipulate that connection for their own advancement, frequently by lying egregiously; and threaten established rules of conduct and constraining institutions as enemies of the popular will that they embody.
A modular microarray imaging system for highly specific COVID-19 antibody testing
The London school’s MBA is ranked first in Europe, its EMBA programme, delivered jointly with Columbia Business School in the US, is ranked third and its MiM programme is in the top 10 on its first participation. The MiM ranking was the last missing piece for LBS to come first in Europe.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
The statement said: "We sincerely apologize to Moonlight, La La Land, Warren Beatty, Faye Dunaway, and Oscar viewers for the error that was made during the award announcement for Best Picture."
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
6. It’s not that the story ended badly; it’s that we expect too much of the story.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Mr Mallaby’s 800-page book was published in October by Bloomsbury and Penguin Press, and was hailed as “exceptional” in an FT review. It came up against strong competition from five other shortlisted books tackling the world’s critical economic and management challenges — from the US productivity gap to persistent gender imbalances.
Amazon joins the innovators list for the first time for innovations in data centers, devices, electronic methods and systems, according to its latest report.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
But Gitanjali's portable invention allows a sensor linked to a mobile app to give an accurate, almost immediate analysis.
Everyone has both, but people tend to be most attached to their “best” identity — the one that offers the most social status or privileges. Successful professionals, for example, often define their identities primarily through their careers.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
The other two tweets from Obama that made the list were posted when he was leaving the office.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
In the big closing session of the World Economic Forum in Davos, they recognised risks existed and badly run emerging markets might be vulnerable to shocks, but concluded that the outlook was brighter than it has been for many years.
‘Jordan,’ ‘harley,’ ‘robert,’ ‘matthew,’ ‘daniel,’ ‘andrew,’ ‘andrea,’ and ‘joshua’ all made it on the list – along with ‘football,’ and ‘lakers.’
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Except your Watson, he thinks it's hot.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
A spokeswoman for Harvard University declined to comment on the report. "We do not comment publicly on the admissions status of individual applicants," Rachael Dane wrote in an email.
Recipient: Kim Kardashian
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
"There are ways to control air (pollution), but we need stronger determination to control it." ZHANG LIJUN, member of the CPPCC National Committee and former vice-minister of environmental protection
Anti-HIV drug repurposing against SARS-CoV-2
Piggyback riders are designed especially for small children and toddlers, to lessen the parents’ struggles.
Length-scale dependence of protein hydration-shell density
"The CPI just went up two percent year on year in 2016, less than the three-percent predictive index. It was a moderate inflation, and reflected the price level was effectively controlled and basically stable," said Jin.
50个最优秀的“无工作经验要求”项目的所有毕业生中，三分之一以上毕业于英国的商学院。英国的商学院还吸引了近一半的女学生以及近一半的国际学生。实际上，2014年一个英国“无工作经验要求”金融硕士项目招收的学生中，有94%来自海外。这些学生当中约有85%来自欧洲经济区(European Economic Area)以外，55%来自中国内地。
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
What would he try for his solo move: "Sweet Creature" and "Ever Since New York" are intimate acoustic ballads; while "Kiwi" lets him strut his Oasis-style self at top volume. "Two Ghosts" is a break-up lament .
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Steven Spielberg directs Meryl Streep and Tom Hanks in The Post, a thrilling drama about the unlikely partnership between The Washington Post's Katharine Graham (Streep), the first female publisher of a major American newspaper, and editor Ben Bradlee (Hanks), as they race to catch up with The New York Times to expose a massive cover-up of government secrets that spanned three decades and four U.S. Presidents. The two must overcome their differences as they risk their careers - and their very freedom - to help bring long-buried truths to light.
About this collection
In March, Ford completed its exit from the luxury car market by selling Volvo to China's Geely Automobile for $1.6 billion. Although the sale represents a sharp loss - the company paid $6 billion for the Swedish automaker eleven years ago - Ford posted an annual profit of $2.7 billion in 2009, its first profitable year since 2005. Assisted by the 'Cash for Clunkers' program (not to mention Toyota's accelerator woes), Ford recaptured its position as the nation's largest carmaker in February. Which is why Ford's CEO Alan Mulally can now look abroad, including big markets like India, where it recently introduced the compact Figo.